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Skin Signs & Symptoms CenterSome skin signs and symptoms - such as skin rash, pruritus, anal itching, skin boils, moles, ulcers and bruised hands and arms - can indicate anything from a relatively harmless condition to more serious disorders. Other indicators are associated with specific disorders. The rash erythema marginatum indicates rheumatic fever, while erythema migrans indicates Lyme disease. Health Guides
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